Iontophoresis Vitamin C



In the conventional product administration method, it was difficult for the ingredients to penetrate deep in skin and to fully exert their beautifying effect and skin protection effect.

Iontophoresis is a method to penetrate an ionized solvent into skin deeply by passing feeble current through skin has been emerging as a new skin care method from several years ago. This treatment is safe, effective, and affordable. 

SKIN LIGHTENING WITH IONTOPHORESIS  OF L-ASCORBIC ACID 2-PHOSPHATE (Vitamin C)
Some acquired pigmentation, including melasma and postinflammatory hyperpigmentation, do not respond well to or even worsen after surgical treatment such as laser therapy. These lesions are best treated conservatively with topical whitening agents and iontophoresis of L-ascorbic acid 2-phosphate. Iontophoresis of L-ascorbic acid 2-phosphate is a safe, convenient, and effective method of treatment. This treatment is safe, effective, and affordable.

Effectiveness
The high effectiveness of iontophoresis in treatment function:

A.

Sufficient amount of vitamin C should be supplied to the basal layer of epidermis to suppress abnormal increase in melanin that causes pigmentation such as chloasma, freckle, and transient pigmentation (after laser irradiation) and to decolorize already-existing melanin.
B.

Wrinkle – it is required to hydrate proline/lycine residue in alpha-chains to form triple helix by the polymerization of 3 pieces of preprocollagen alpha-chains regarding dermis fibroblast. It is significant to supply vitamin C intentionally as an essential cofactor to make propyl-4-hydroxylase function as a main enzyme to catalyze the reaction above because Vitamin C is apt to be depleted partially.
C.

Elimination of active oxygen – the elimination of active oxygen by intracellular Vitamin C can prevent deep-penetrating UVA-wave from causing nuclear DNA double-strand breaks and damage to DNA base components such as 8-OHdG.
D.

Prevention of skin aging – Provitamin C can be, in the DNA level, an age resistor that significantly extends cell life by preventing telomere DNA located at both ends of chromosomes from shortening.
E.

Hyperoxidation of sebum such as squalene and ceramide has a deletrious effect on skin. Provitamin C prevents cell death caused by lipoperoxide.

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